Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
| ▸ | LONP1 | P36776 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869418 | 1.00 | DPP8 (0.36) | DPP8DPP7SLC15A1CPB2DPP4 | |
| SCHEMBL8870237 | 0.90 | DPP8 (0.38) | DPP8DPP7CPB2DPP4LONP1 | |
| SCHEMBL8870244 | 0.90 | DPP8 (0.38) | DPP8DPP7CPB2DPP4LONP1 | |
| SCHEMBL8869661 | 0.82 | SMYD3 (0.33) | DPP4XIAP | |
| SCHEMBL8869666 | 0.82 | SMYD3 (0.33) | DPP4XIAP | |
| SCHEMBL8869276 | 0.81 | DPP4 (0.35) | DPP4 | |
| SCHEMBL8869272 | 0.81 | DPP4 (0.35) | DPP4 | |
| SCHEMBL8870452 | 0.81 | DPP4 (0.37) | DPP8DPP7SLC15A1DPP4 | |
| SCHEMBL8870455 | 0.81 | DPP4 (0.37) | DPP8DPP7SLC15A1DPP4 | |
| SCHEMBL8870895 | 0.80 | DPP8 (0.38) | DPP8DPP7SLC15A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624924-A | Quinobenzothiazine antineoplastic agents | ABBOTT LABORATORIES (US) | 1997-04-29 | — | — | US | claimed |
| US-5318965-A | Administering to treat leukemia, melanoma, carcinoma of lung, colon, ovaries | ABBOTT LABORATORIES (US) | 1994-06-07 | — | — | US | claimed |
| WO-1993016702-A1 | QUINOBENZOXAZINE, QUINOBENZOTHIAZINE, AND PYRIDO-ACRIDINE ANTINEOPLASTIC AGENTS | ABBOTT LABORATORIES (US) | 1993-09-02 | — | — | WO | claimed |
| US-5624924-A | Quinobenzothiazine antineoplastic agents | ABBOTT LABORATORIES (US) | 1997-04-29 | — | — | US | disclosed |
| US-5318965-A | Administering to treat leukemia, melanoma, carcinoma of lung, colon, ovaries | ABBOTT LABORATORIES (US) | 1994-06-07 | — | — | US | disclosed |