Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221010 | 0.85 | KDM4E (0.48) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL11156533 | 0.85 | HCAR2 (0.53) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL8625297 | 0.83 | HCAR2 (0.59) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL27534210 | 0.83 | HCAR2 (0.59) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL8625307 | 0.83 | HCAR2 (0.59) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL6966049 | 0.82 | HCAR2 (0.69) | HCAR2KMT2AALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL10983709 | 0.82 | ESR1 (0.50) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL29770346 | 0.81 | ESR1 (0.46) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL27704799 | 0.80 | HCAR2 (0.49) | ESR1ESR2HCAR2KMT2ALMNA | |
| SCHEMBL21843922 | 0.80 | ESR1 (0.49) | ESR1ESR2HCAR2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594132-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| US-5026695-A | Gram negative-gram positive microbiocides, oral adminis tration | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4904652-A | 7-acylamino-3-substituted cephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0029557-B1 | 7-ACYLAMINO-3-SUBSTITUTED CEPHALOSPORANIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-03-13 | — | — | EP | disclosed |
| US-4464369-A | CEPHALOSPORINS, ANTIMICROBIALS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| US-4462999-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| EP-0108977-A2 | Starting compounds for preparing 7-acylamino-3-substituted cephalosporanic acid derivatives and process for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-23 | — | — | EP | disclosed |
| US-4409215-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0088385-A2 | 7-Acylamino-3-cephem-4-carboxylic acid derivatives, processes for the preparation of the same and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-14 | — | — | EP | disclosed |
| EP-0029557-A2 | 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-03 | — | — | EP | disclosed |
| US-4097670-A | ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1978-06-27 | — | — | US | disclosed |