SCHEMBL886953

SCHEMBL886953

CCO[SiH](/C=C/c1ccccc1)CC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.46
TRPA1 O75762 1/20 0.37
MAOB P27338 2/20 0.37
CYP1A2 P05177 2/20 0.37
RAB9A P51151 2/20 0.37
CYP3A4 P08684 1/20 0.37
THPO P40225 1/20 0.37
HIF1A Q16665 1/20 0.37
MTOR P42345 1/20 0.37
MAOA P21397 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
IDO1 P14902 2/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GMNN O75496 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL886954 1.00 RELA (0.46) RELATRPA1MAOBCYP1A2RAB9A
SCHEMBL886959 0.83 RELA (0.43) RELATRPA1MAOBCYP1A2RAB9A
SCHEMBL73089 0.81 RELA (0.48) RELATRPA1MAOBCYP1A2RAB9A
SCHEMBL3472343 0.79 MTOR (0.41) RELACYP1A2RAB9ACYP3A4THPO
SCHEMBL6553090 0.74 MAOB (0.44) RELATRPA1MAOBRAB9ACYP3A4
SCHEMBL15302240 0.71 RELA (0.41) RELATRPA1MAOBCYP1A2CTDSP1
SCHEMBL6114582 0.71 RELA (0.41) RELATRPA1MAOBCYP1A2CYP3A4
SCHEMBL886948 0.71 NPC1 (0.42) RELAMAOBCYP1A2ALDH1A1LMNA
SCHEMBL886947 0.71 NPC1 (0.42) RELAMAOBCYP1A2ALDH1A1LMNA
SCHEMBL72198 0.70 RELA (0.46) RELATRPA1MAOBIDO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833905-B1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER MICHELIN & CIE (FR) 2013-08-07 EP claimed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US claimed
US-20110021702-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-01-27 US claimed
US-7820771-B2 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S. A. (CH) 2010-10-26 US claimed
EP-1838765-B1 FUNCTIOANALISED POLYVINYLAROMATIC NANOPARTICLES MICHELIN RECH TECH (CH) 2010-08-04 EP claimed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US claimed
US-20090270558-A1 Functionalized Polyvinylaromatic Nanoparticles MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-10-29 US claimed
EP-2044148-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER Societe de Technologie Michelin (FR) 2009-04-08 EP claimed
EP-2041207-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES Societe de Technologie Michelin STM (FR) 2009-04-01 EP claimed
US-20080132644-A1 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-06-05 US claimed
WO-2008003435-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO claimed
WO-2008003434-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO claimed
EP-1838765-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES Michelin Recherche et Technique S.A. (CH) 2007-10-03 EP claimed
EP-1833905-A1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER Societe de Technologie Michelin (FR) 2007-09-19 EP claimed
WO-2006069793-A1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO claimed
WO-2006069792-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO claimed
EP-2044148-B1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN & CIE (FR) 2017-04-05 EP disclosed
US-8883929-B2 Functionalized vinyl polymer nanoparticles COMPAGNIE GENERALE DES ETABLISSEMENTS (FR) 2014-11-11 US disclosed
WO-2006069793-A1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO disclosed
WO-2006069792-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO disclosed