Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868877 | 0.92 | SMN1; SMN2 (0.50) | P4HTMHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8869015 | 0.91 | P4HTM (0.48) | P4HTMSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL8868684 | 0.90 | P4HTM (0.47) | P4HTMHSD17B10SMN1; SMN2 | |
| SCHEMBL8869595 | 0.90 | P4HTM (0.49) | P4HTMHSD17B10MEN1KMT2ALOX | |
| SCHEMBL8869265 | 0.89 | P4HTM (0.47) | P4HTMHSD17B10MEN1KMT2ALOX | |
| SCHEMBL8870268 | 0.88 | P4HTM (0.47) | P4HTMHSD17B10MEN1KMT2ALOX | |
| SCHEMBL8869078 | 0.88 | P4HTM (0.53) | P4HTMKMT2AEGFRFLT1FLT4 | |
| SCHEMBL8868272 | 0.87 | P4HTM (0.48) | P4HTMSMN1; SMN2KMT2AEGFRCASP3 | |
| SCHEMBL8869014 | 0.87 | P4HTM (0.54) | P4HTMSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL8869658 | 0.87 | HTT (0.57) | P4HTMHSD17B10NAMPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |