Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869859 | 1.00 | DPP4 (0.47) | DPP4KCNH2SCN3AKDM1ALMNA | |
| SCHEMBL30890546 | 0.83 | KCNH2 (0.60) | DPP4KCNH2SCN3ALMNASCN1A | |
| SCHEMBL21439771 | 0.78 | KCNH2 (0.46) | DPP4KCNH2SCN3AKDM1ASCN1A | |
| SCHEMBL12571278 | 0.78 | KCNH2 (0.54) | DPP4KCNH2SCN3ASCN1ASCN4A | |
| SCHEMBL13447270 | 0.78 | KCNH2 (0.54) | DPP4KCNH2SCN3ASCN1ASCN4A | |
| SCHEMBL135106 | 0.77 | KCNH2 (0.56) | DPP4KCNH2SCN3ASCN1ASCN4A | |
| SCHEMBL197425 | 0.77 | KCNH2 (0.56) | DPP4KCNH2SCN3ASCN1ASCN4A | |
| SCHEMBL5696388 | 0.77 | KCNH2 (0.56) | DPP4KCNH2SCN3ASCN1ASCN4A | |
| SCHEMBL1226045 | 0.77 | KCNH2 (0.56) | DPP4KCNH2SCN3ASCN1ASCN4A | |
| SCHEMBL135105 | 0.77 | KCNH2 (0.56) | DPP4KCNH2SCN3ASCN1ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |