Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869892 | 1.00 | ACE (0.43) | ACEMMESIGMAR1 | |
| SCHEMBL8871191 | 0.89 | ACE (0.53) | ACEMME | |
| SCHEMBL8870406 | 0.89 | ACE (0.53) | ACEMME | |
| SCHEMBL8668741 | 0.89 | ACE (0.53) | ACEMME | |
| SCHEMBL8870137 | 0.88 | SIGMAR1 (0.50) | ACEMMESIGMAR1 | |
| SCHEMBL8870127 | 0.88 | SIGMAR1 (0.50) | ACEMMESIGMAR1 | |
| SCHEMBL8871413 | 0.86 | ACE (0.48) | ACEMMESIGMAR1 | |
| SCHEMBL8870010 | 0.83 | ABCB1 (0.43) | — | |
| SCHEMBL8870026 | 0.83 | ABCB1 (0.43) | — | |
| SCHEMBL8870146 | 0.81 | CYP3A4 (0.41) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |