Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13133350 | 1.00 | MAPT (0.57) | MAPTKDM4EALDH1A1THRBTDP1 | |
| SCHEMBL25376731 | 0.82 | MAPT (0.52) | MAPTKDM4EALDH1A1THRBTDP1 | |
| SCHEMBL21715596 | 0.80 | MAPT (0.46) | MAPTKDM4EALDH1A1THRBTDP1 | |
| SCHEMBL11089874 | 0.79 | CA12 (0.57) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL11089873 | 0.79 | CA12 (0.57) | MAPTKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL19228736 | 0.78 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL10309895 | 0.78 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1TDP1HPGD | |
| SCHEMBL11977409 | 0.77 | MAPT (0.59) | MAPTKDM4EALDH1A1THRBTDP1 | |
| SCHEMBL13881090 | 0.77 | MAPT (0.57) | MAPTKDM4EALDH1A1THRBTDP1 | |
| Norletimol SCHEMBL6436311 | 0.77 | MAPT (0.77) | MAPTKDM4EALDH1A1THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |