Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.66 |
| ▸ | FLT3 | P36888 | 6/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335235 | 0.91 | PDGFRB (0.79) | KMT2APDGFRBPDGFRAFLT3CYP1A2 | |
| SCHEMBL8869244 | 0.88 | KMT2A (0.78) | KMT2AXDHPDGFRBPDGFRAFLT3 | |
| SCHEMBL9513175 | 0.88 | KMT2A (1.00) | KMT2AXDHPDGFRBPDGFRAFLT3 | |
| SCHEMBL31287858 | 0.85 | KMT2A (0.78) | KMT2AXDHPDGFRBPDGFRAFLT3 | |
| SCHEMBL9816551 | 0.85 | KMT2A (0.78) | KMT2AXDHPDGFRBPDGFRAFLT3 | |
| SCHEMBL4263996 | 0.85 | PDGFRB (0.61) | KMT2APDGFRBPDGFRAFLT3CYP1A2 | |
| SCHEMBL8868735 | 0.82 | RAB9A (0.85) | KMT2AXDHPDGFRBPDGFRAFLT3 | |
| SCHEMBL31287830 | 0.82 | KMT2A (0.72) | KMT2AXDHPDGFRBPDGFRAFLT3 | |
| SCHEMBL31287750 | 0.81 | KMT2A (0.72) | KMT2AXDHFLT3CYP1A2CYP2C9 | |
| SCHEMBL6866887 | 0.80 | PDGFRB (1.00) | KMT2APDGFRBPDGFRAFLT3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637593-A | MIGRAINE; HYPOTENSIVE AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-06-10 | — | — | US | disclosed |