Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870521 | 1.00 | POLB (0.51) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL6185805 | 0.87 | HSD17B10 (0.54) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL13091656 | 0.87 | HSD17B10 (0.54) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL14024616 | 0.87 | HSD17B10 (0.54) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL3072035 | 0.87 | HSD17B10 (0.54) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL5713194 | 0.85 | GAA (0.72) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL4316372 | 0.82 | POLB (0.49) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL8870492 | 0.77 | KDM4E (0.46) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL9250150 | 0.77 | KDM4E (0.46) | POLBGAARAB9AHSD17B10FFAR2 | |
| SCHEMBL3826056 | 0.77 | KDM4E (0.46) | POLBGAARAB9AHSD17B10FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |