Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827938 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1POLBGAARAB9A | |
| SCHEMBL9250150 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1POLBGAARAB9A | |
| SCHEMBL3826056 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1POLBGAARAB9A | |
| SCHEMBL9264341 | 0.90 | GPR119 (0.42) | KDM4EALDH1A1GPR119 | |
| SCHEMBL9645053 | 0.90 | GPR119 (0.42) | KDM4EALDH1A1GPR119 | |
| SCHEMBL9271459 | 0.89 | ALDH1A1 (0.45) | KDM4EALDH1A1POLBGPR119 | |
| SCHEMBL14024616 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 | |
| SCHEMBL6185805 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 | |
| SCHEMBL3072035 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 | |
| SCHEMBL13091656 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | disclosed |