Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034755 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL3059385 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL5526027 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL2029800 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL31714043 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL5490059 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL2034753 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL3832268 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL16079679 | 0.84 | KDM4E (0.69) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 | |
| SCHEMBL3832263 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHSD17B10S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |