Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437696 | 0.94 | ALDH1A1 (0.60) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| Ethyl Acetate SCHEMBL10620330 | 0.80 | ALDH1A1 (0.82) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| SCHEMBL11808669 | 0.78 | ALDH1A1 (0.60) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| SCHEMBL6314407 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| SCHEMBL2161093 | 0.78 | — | — | |
| SCHEMBL2308025 | 0.76 | SOAT1 (0.70) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| Diethyl Pyrocarbonate SCHEMBL8342707 | 0.76 | SOAT1 (0.79) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| SCHEMBL8332085 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| SCHEMBL15413048 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HSD17B10LMNASOAT1TSHR | |
| SCHEMBL27651053 | 0.76 | SOAT1 (0.70) | ALDH1A1HSD17B10LMNASOAT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107272-A1 | SYNTHETIC METHODS AND DERIVATIVES OF TRIPHOSPHATE OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| EP-2344514-A2 | SYNTHETIC METHODS AND DERIVATIVES OF TRIPHOSPHATE OLIGONUCLEOTIDES | Alnylam Pharmaceuticals Inc. (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010028079-A2 | SYNTHETIC METHODS AND DERIVATIVES OF TRIPHOSPHATE OLIGONUCLEOTIDES | ALNYLAM PHARMACEUTICALS, INC (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107272-A1 | SYNTHETIC METHODS AND DERIVATIVES OF TRIPHOSPHATE OLIGONUCLEOTIDES | IFNAR1, DDX18, STING1 | ALDH1A1 1536/4885HSD17B10 4303/4885LMNA 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.