Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692556 | 0.87 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL19677122 | 0.85 | SLC1A3 (0.42) | SLC6A2SLC6A4SLC6A3IDO1MEN1 | |
| SCHEMBL23476703 | 0.85 | CYP1A2 (0.50) | SLC6A2SLC6A4SLC6A3IDO1TDO2 | |
| SCHEMBL11100448 | 0.81 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL10334898 | 0.79 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL15061660 | 0.79 | CA7 (0.42) | SLC6A2SLC6A4SLC6A3MEN1SLC1A3 | |
| SCHEMBL9291604 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL28505841 | 0.74 | CHRNB2 (0.65) | SLC6A2SLC6A4SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL4058254 | 0.73 | PPARG (0.49) | SLC6A2SLC6A4SLC6A3CNR2PPARG | |
| SCHEMBL6832293 | 0.73 | TSHR (0.50) | SLC6A2SLC6A4SLC6A3POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698567-A | LIPOXYGENASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1997-12-16 | — | — | US | disclosed |