Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 6/20 | 0.53 |
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30787524 | 0.84 | MAOB (0.73) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL8869586 | 0.84 | MAOB (0.58) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787466 | 0.84 | MAOB (0.58) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL28902190 | 0.83 | MAOB (0.79) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30167103 | 0.83 | MAOB (0.79) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787472 | 0.81 | MAOB (0.60) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787475 | 0.80 | MAOB (0.54) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787487 | 0.80 | MAOB (0.62) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30787497 | 0.77 | MAOB (0.55) | MAOBMAOACA12CA9CA1 | |
| SCHEMBL30167104 | 0.76 | HSD17B3 (0.63) | MAOBMAOACA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607928-A | Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives | ZENECA LIMITED (GB) | 1997-03-04 | — | — | US | disclosed |
| EP-0695753-A1 | Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |