SCHEMBL30787487

SCHEMBL30787487

Cc1cc2occ(CNc3ccccc3)c(=O)c2cc1C

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.62
MAOA P21397 1/20 0.62
CA12 O43570 4/20 0.51
CA9 Q16790 4/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
KMT2A Q03164 2/20 0.50
ALOX15 P16050 1/20 0.47
TNF P01375 1/20 0.46
TNFSF11 O14788 1/20 0.44
AIMP2 Q13155 1/20 0.43
HSD17B3 P37058 1/20 0.42
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
ALB P02768 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30787497 0.83 MAOB (0.55) MAOBMAOACA12CA9CA1
SCHEMBL28902190 0.81 MAOB (0.79) MAOBMAOACA12CA9CA1
SCHEMBL30167103 0.81 MAOB (0.79) MAOBMAOACA12CA9CA1
SCHEMBL30787524 0.80 MAOB (0.73) MAOBMAOACA12CA9CA1
SCHEMBL8871016 0.80 MAOB (0.58) MAOBMAOACA12CA9CA1
SCHEMBL28902168 0.80 HSD17B3 (0.63) MAOBMAOACA12CA9CA1
SCHEMBL8869586 0.80 MAOB (0.58) MAOBMAOACA12CA9CA1
SCHEMBL30167104 0.80 HSD17B3 (0.63) MAOBMAOACA12CA9CA1
SCHEMBL30787466 0.80 MAOB (0.58) MAOBMAOACA12CA9CA1
SCHEMBL30787472 0.80 MAOB (0.60) MAOBMAOACA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567419-A Synthesis method of 3-amine methyl primary ketone derivative 深圳职业技术大学 2024-02-20 CN disclosed