Known targets — ChEMBL curated mechanism
ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL3389955 | 0.97 | LMNA (0.59) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL3385393 | 0.94 | LMNA (0.47) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL3710793 | 0.89 | LMNA (0.65) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL547729 | 0.88 | LMNA (0.62) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL2229853 | 0.86 | LMNA (0.65) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL9142009 | 0.85 | LMNA (0.59) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL826558 | 0.84 | LMNA (0.62) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL303216 | 0.84 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL21835970 | 0.84 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL2266761 | 0.84 | LMNA (0.77) | LMNAPDE4AUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434869-B1 | METHOD FOR PREPARING CALCIUM GLUCONATE | PURAC BIOCHEM NV (NL) | 2010-12-15 | — | — | EP | claimed |
| US-20090104339-A1 | METHOD FOR PREPARING CALCIUM GLUCONATE | PURAC BIOCHEM B.V. (NL) | 2009-04-23 | — | — | US | claimed |
| US-20040253345-A1 | Method for preparing calcium gluconate | PURAC BIOCHEM B.V. (NL) | 2004-12-16 | — | — | US | claimed |
| EP-2405770-A1 | COMPOSITIONS COMPRISING MONATIN AND CALCIUM | Cargill, Incorporated (US) | 2012-01-18 | — | — | EP | disclosed |
| US-20120009320-A1 | COMPOSITIONS COMPRISING MONATIN AND CALCIUM | CARGILL, INCORPORATED | 2012-01-12 | — | — | US | disclosed |
| WO-2010105014-A1 | COMPOSITIONS COMPRISING MONATIN AND CALCIUM | CARGILL, INCORPORATED (US) | 2010-09-16 | — | — | WO | disclosed |
| CN-100451124-C | Method for preparing calcium gluconate | PURAC BIOCHEM NV (NL) | 2009-01-14 | — | — | CN | disclosed |
| CN-1564871-A | Method for preparing calcium gluconate | PURAC BIOCHEM NV (NL) | 2005-01-12 | — | — | CN | disclosed |