Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275178 | 0.91 | HTR1A (0.60) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| SCHEMBL8870963 | 0.90 | HTR1A (0.59) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| SCHEMBL8870113 | 0.81 | HTR1A (0.63) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| SCHEMBL8871523 | 0.81 | HTR1A (0.59) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| Hydrochloric Acid SCHEMBL8871647 | 0.79 | HTR1A (0.66) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| Escholtzine SCHEMBL29406066 | 0.78 | HTR1A (1.00) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| Escholtzine SCHEMBL29692675 | 0.78 | HTR1A (1.00) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| SCHEMBL8871943 | 0.76 | HTR1A (0.52) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| SCHEMBL8872180 | 0.75 | HTR1A (0.55) | HTR1ACYP3A4DRD1DRD2ADRA1A | |
| SCHEMBL8871833 | 0.74 | HTR1A (0.51) | HTR1ACYP3A4DRD1DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648359-A | ESCHSCHOLTZINE AND DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0663210-A2 | Tumor necrosis factor production inhibitors | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |