SCHEMBL887145

SCHEMBL887145

O=C1N=C(C(=O)O)CS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14472921 0.65 HCAR2 (0.33)
SCHEMBL3928670 0.57
SCHEMBL2025314 0.51
SCHEMBL17848807 0.51 DHODH (0.47)
SCHEMBL29223372 0.48 TSHR (0.36)
Mellitic Acid SCHEMBL28758936 0.48 CYP1A2 (0.47)
SCHEMBL3506509 0.46
Bicarbonate SCHEMBL8535954 0.45 CA1 (0.83)
Bicarbonate SCHEMBL5458669 0.45
Bicarbonate SCHEMBL853 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022173759-A1 COMPOSITIONS OF HYDROXY ACIDS WITH SALICYLIC ACID AND USES THEREFORE Able Derm LLC (US) 2022-08-18 WO claimed
EP-2405886-A1 TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Isp Investments Inc. (US) 2012-01-18 EP claimed
WO-2010105052-A1 TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2010-09-16 WO claimed
JP-6145054-A None JP disclosed
US-12115173-B2 Compositions of hydroxy acids with salicylic acid and uses therefore ELBA LABORATORIES (US) 2024-10-15 US disclosed
WO-2022173759-A1 COMPOSITIONS OF HYDROXY ACIDS WITH SALICYLIC ACID AND USES THEREFORE Able Derm LLC (US) 2022-08-18 WO disclosed
US-20220249519-A1 COMPOSITIONS OF HYDROXY ACIDS WITH SALICYLIC ACID AND USES THEREFORE ELBA LABORATORIES 2022-08-11 US disclosed
CN-108295073-B Polyfluoro compounds as bruton's tyrosine kinase inhibitors 浙江导明医药科技有限公司 2020-06-16 CN disclosed
EP-2405886-B1 TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC (US) 2017-09-27 EP disclosed
EP-2405886-A1 TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF Isp Investments Inc. (US) 2012-01-18 EP disclosed
WO-2010105052-A1 TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2010-09-16 WO disclosed
JP-H06145054-A METHOD FOR TREATING RE-PERFUSION DAMAGE AND COMPOSITION THEREFOR CLINTEC NUTRITION CO 1994-05-24 JP disclosed