⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708165 | 0.68 | ITGB3 (0.39) | — | |
| SCHEMBL27256008 | 0.62 | — | — | |
| SCHEMBL11531223 | 0.62 | — | — | |
| SCHEMBL5070284 | 0.62 | — | — | |
| SCHEMBL9422395 | 0.62 | — | — | |
| SCHEMBL30322825 | 0.59 | — | — | |
| SCHEMBL3489509 | 0.59 | — | — | |
| SCHEMBL8741732 | 0.57 | — | — | |
| SCHEMBL887145 | 0.57 | — | — | |
| SCHEMBL10717760 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038253-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | Arrow Therapeutics Limited (GB) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007138242-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2007-12-06 | — | — | WO | disclosed |