Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 15/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872997 | 0.95 | LTB4R2 (0.45) | LTB4R2AGTR1 | |
| SCHEMBL8873614 | 0.90 | LTB4R2 (0.40) | LTB4R2AGTR1FFAR1AKR1B1AGTR2 | |
| SCHEMBL8872195 | 0.87 | NR1H4 (0.38) | CTSAFFAR1AKR1B1NR1H4 | |
| SCHEMBL8873063 | 0.87 | LTB4R2 (0.40) | LTB4R2AGTR1FFAR1AKR1B1PPARG | |
| SCHEMBL8875659 | 0.86 | LTB4R2 (0.42) | LTB4R2AGTR1FFAR1AKR1B1NR1H4 | |
| SCHEMBL8874016 | 0.85 | LTB4R2 (0.45) | LTB4R2AGTR1 | |
| SCHEMBL8872878 | 0.84 | LTB4R2 (0.40) | LTB4R2AGTR1FFAR1AKR1B1PPARG | |
| SCHEMBL8872445 | 0.82 | LTB4R2 (0.45) | LTB4R2AGTR1 | |
| SCHEMBL8873498 | 0.82 | LTB4R2 (0.41) | LTB4R2AGTR1FFAR1AKR1B1PPARG | |
| SCHEMBL8872815 | 0.81 | LTB4R2 (0.47) | LTB4R2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700938-A | Intermediates for imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5608068-A | Process for the preparation of imidazopyridine derivatives and intermediates | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0627433-A1 | PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE | Eisai Co., Ltd. (JP) | 1994-12-07 | — | — | EP | disclosed |