SCHEMBL8874016

SCHEMBL8874016

CCCCC(=O)N(Cc1ccc(-c2ccccc2C#N)cc1)c1ncc(Br)c(C)c1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 20/20 0.45
AGTR1 P30556 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8873614 0.95 LTB4R2 (0.40) LTB4R2AGTR1
SCHEMBL8872997 0.91 LTB4R2 (0.45) LTB4R2AGTR1
SCHEMBL8872476 0.87 LTB4R2 (0.45) LTB4R2AGTR1
SCHEMBL8872815 0.86 LTB4R2 (0.47) LTB4R2AGTR1
SCHEMBL8958538 0.86 LTB4R2 (0.35) LTB4R2AGTR1
SCHEMBL8872011 0.85 LTB4R2 (0.40) LTB4R2AGTR1
SCHEMBL8873981 0.85 LTB4R2 (0.59) LTB4R2AGTR1
SCHEMBL9854241 0.85 LTB4R2 (0.46) LTB4R2AGTR1
SCHEMBL8872931 0.85 ABL1 (0.37)
SCHEMBL9854253 0.85 AGTR1 (0.45) AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700938-A Intermediates for imidazopyridine derivatives EISAI CO., LTD. (JP) 1997-12-23 US disclosed
US-5618969-A Intermediates for imidazopyridines EISAI CO., LTD. (JP) 1997-04-08 US disclosed
US-5608068-A Process for the preparation of imidazopyridine derivatives and intermediates EISAI CO., LTD. (JP) 1997-03-04 US disclosed
US-5587504-A Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates EISAI CO., LTD. (JP) 1996-12-24 US disclosed
US-5583229-A Process for the preparation of imidazopyridine derivatives EISAI CO., LTD. (JP) 1996-12-10 US disclosed
US-5559236-A Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists EISAI CO., LTD. (JP) 1996-09-24 US disclosed
US-5557002-A Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists EISAI CO., LTD. (JP) 1996-09-17 US disclosed
US-5554757-A Process for the preparation of imidazopyridine derivatives, and intermediates therefore EISAI CO., LTD. (JP) 1996-09-10 US disclosed
EP-0627433-A1 PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE Eisai Co., Ltd. (JP) 1994-12-07 EP disclosed
EP-0426021-A1 Condensed imidazole derivatives and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-05-08 EP disclosed