SCHEMBL8872129

SCHEMBL8872129

CC(C)c1c(Cl)c(C(=O)O)cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9396145 0.89 NOTUM (0.30) NOTUM
SCHEMBL20356681 0.78 NOTUM (0.36) NOTUM
SCHEMBL6899016 0.78 NOTUM (0.35) NOTUM
SCHEMBL8993676 0.77 NOTUM (0.31) NOTUM
SCHEMBL2976620 0.77 NOTUM (0.34) NOTUM
SCHEMBL20356744 0.75 NOTUM (0.36) NOTUM
SCHEMBL14360567 0.73 MYC (0.54) NOTUM
SCHEMBL8872127 0.73 NOTUM (0.33) NOTUM
SCHEMBL6425876 0.72 DHODH (0.33)
SCHEMBL5691574 0.72 DHODH (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599771-A PREEMERGENCE, POSTEMERGENCE CIBA-GEIGY CORPORATION (US) 1997-02-04 US disclosed
WO-1994024128-A1 3-ARYLURACIL DERIVATIVES AND THEIR USE AS HERBICIDES CIBA-GEIGY AG (CH) 1994-10-27 WO disclosed