SCHEMBL8993676

SCHEMBL8993676

CC(C)c1c(-n2c(=S)cc(C(F)(F)F)n(C)c2=O)cc(C(=O)O)c(Cl)c1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8872129 0.77 NOTUM (0.32) NOTUM
SCHEMBL8993529 0.74 TDP1 (0.50) NOTUM
SCHEMBL6899016 0.70 NOTUM (0.35) NOTUM
SCHEMBL8993673 0.69 PDK2 (0.33)
SCHEMBL9396145 0.69 NOTUM (0.30) NOTUM
SCHEMBL2976620 0.68 NOTUM (0.34) NOTUM
SCHEMBL20356681 0.68 NOTUM (0.36) NOTUM
SCHEMBL20356744 0.66 NOTUM (0.36) NOTUM
SCHEMBL8872127 0.65 NOTUM (0.33) NOTUM
SCHEMBL10410422 0.65 MEN1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5527764-A 3-arylthionouracils useful as herbicides, defoliants, and desiccants UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-06-18 US disclosed