Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 12/20 | 0.54 |
| ▸ | BDKRB1 | P46663 | 5/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872316 | 0.95 | LTB4R2 (0.62) | LTB4R2BDKRB1AGTR1 | |
| SCHEMBL8873828 | 0.87 | LTB4R2 (0.54) | LTB4R2BDKRB1NR1H4AGTR1AGTR2 | |
| SCHEMBL8872739 | 0.86 | LTB4R2 (0.52) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL8873210 | 0.86 | LTB4R2 (0.43) | LTB4R2BDKRB1NR1H4AGTR1AGTR2 | |
| SCHEMBL8875659 | 0.84 | LTB4R2 (0.42) | LTB4R2NR1H4AGTR1AGTR2 | |
| SCHEMBL8874430 | 0.83 | LTB4R2 (0.52) | LTB4R2BDKRB1AGTR1AGTR2 | |
| SCHEMBL8873284 | 0.83 | LTB4R2 (0.61) | LTB4R2AGTR1 | |
| SCHEMBL8873981 | 0.81 | LTB4R2 (0.59) | LTB4R2BDKRB1AGTR1 | |
| SCHEMBL8872815 | 0.79 | LTB4R2 (0.47) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8872577 | 0.78 | LTB4R2 (0.59) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700938-A | Intermediates for imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5608068-A | Process for the preparation of imidazopyridine derivatives and intermediates | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5587504-A | Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates | EISAI CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5583229-A | Process for the preparation of imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5557002-A | Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists | EISAI CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0627433-A1 | PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE | Eisai Co., Ltd. (JP) | 1994-12-07 | — | — | EP | disclosed |