SCHEMBL8873284

SCHEMBL8873284

CCCCC(=O)N(Cc1ccc(-c2ccccc2C(=O)OC)cc1)c1nc(C)cc(C)c1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 20/20 0.61
AGTR1 P30556 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8873828 0.95 LTB4R2 (0.54) LTB4R2AGTR1
SCHEMBL8872316 0.88 LTB4R2 (0.62) LTB4R2AGTR1
SCHEMBL8872577 0.86 LTB4R2 (0.59) LTB4R2AGTR1
SCHEMBL8872352 0.85 LTB4R2 (0.43) LTB4R2
SCHEMBL8873268 0.85 LTB4R2 (0.46) LTB4R2AGTR1
SCHEMBL8873981 0.84 LTB4R2 (0.59) LTB4R2AGTR1
SCHEMBL8873032 0.83 LTB4R2 (0.54) LTB4R2AGTR1
SCHEMBL8874430 0.81 LTB4R2 (0.52) LTB4R2AGTR1
SCHEMBL8873498 0.79 LTB4R2 (0.41) LTB4R2AGTR1
SCHEMBL8872739 0.79 LTB4R2 (0.52) LTB4R2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5700938-A Intermediates for imidazopyridine derivatives EISAI CO., LTD. (JP) 1997-12-23 US disclosed
US-5618969-A Intermediates for imidazopyridines EISAI CO., LTD. (JP) 1997-04-08 US disclosed
US-5608068-A Process for the preparation of imidazopyridine derivatives and intermediates EISAI CO., LTD. (JP) 1997-03-04 US disclosed
US-5587504-A Sulfonyloxy-biphenylcarboxylic ester derivatives which are intermediates EISAI CO., LTD. (JP) 1996-12-24 US disclosed
US-5583229-A Process for the preparation of imidazopyridine derivatives EISAI CO., LTD. (JP) 1996-12-10 US disclosed
US-5559236-A Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists EISAI CO., LTD. (JP) 1996-09-24 US disclosed
US-5557002-A Process for the preparation of biphenyl containing intermediates useful in making angiotensin II receptor antagonists EISAI CO., LTD. (JP) 1996-09-17 US disclosed
US-5554757-A Process for the preparation of imidazopyridine derivatives, and intermediates therefore EISAI CO., LTD. (JP) 1996-09-10 US disclosed
EP-0627433-A1 PROCESS FOR PRODUCING IMIDAZOPYRIDINE DERIVATIVE AND INTERMEDIATE Eisai Co., Ltd. (JP) 1994-12-07 EP disclosed