Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.56 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | NGFR | P08138 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188871 | 1.00 | FTO (0.56) | FTONTRK1NGFRPABPC1CA12 | |
| Bisnafide SCHEMBL29617562 | 0.95 | FTO (0.61) | FTONTRK1NGFRPABPC1CA12 | |
| Bisnafide SCHEMBL9136683 | 0.95 | FTO (0.61) | FTONTRK1NGFRPABPC1CA12 | |
| Bisnafide SCHEMBL9136305 | 0.95 | FTO (0.61) | FTONTRK1NGFRPABPC1CA12 | |
| Bisnafide SCHEMBL9135370 | 0.95 | FTO (0.61) | FTONTRK1NGFRPABPC1CA12 | |
| Bisnafide SCHEMBL9135739 | 0.95 | FTO (0.61) | FTONTRK1NGFRPABPC1CA12 | |
| SCHEMBL9352511 | 0.94 | FTO (0.60) | FTONTRK1NGFRPABPC1CA12 | |
| SCHEMBL9348633 | 0.94 | FTO (0.60) | FTONTRK1NGFRPABPC1CA12 | |
| SCHEMBL9238619 | 0.94 | FTO (0.60) | FTONTRK1NGFRPABPC1CA12 | |
| SCHEMBL9352242 | 0.94 | FTO (0.60) | FTONTRK1NGFRPABPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641782-A | ANTITUMOR AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-06-24 | — | — | US | disclosed |
| US-5585382-A | ANTICARCINOGENIC AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5416089-A | Antitumor agent | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-05-16 | — | — | US | disclosed |