Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392816 | 0.77 | RAB9A (0.46) | MAPK9KMT2AMEN1RAB9AGAA | |
| SCHEMBL8874548 | 0.76 | MAPK9 (0.52) | MAPK9KMT2AMEN1PTGS1PTGS2 | |
| Methane SCHEMBL2343754 | 0.75 | KMT2A (0.47) | MAPK9KMT2AMEN1RAB9APTGS1 | |
| SCHEMBL11459800 | 0.75 | MAPK9 (0.57) | MAPK9KMT2AMEN1RAB9APTGS1 | |
| SCHEMBL29213144 | 0.74 | CYP1A2 (0.48) | MAPK9KMT2AMEN1RAB9AGAA | |
| SCHEMBL7990464 | 0.74 | MAPK9 (0.54) | MAPK9KMT2AMEN1RAB9APTGS1 | |
| SCHEMBL1428266 | 0.74 | GAA (0.49) | KMT2AMEN1RAB9APTGS1PTGS2 | |
| SCHEMBL22722996 | 0.73 | MAPK9 (0.56) | MAPK9KMT2AMEN1RAB9APTGS1 | |
| SCHEMBL29785806 | 0.73 | MAPK9 (0.56) | MAPK9KMT2AMEN1RAB9APTGS1 | |
| SCHEMBL4510613 | 0.73 | MAPK9 (0.56) | MAPK9KMT2AMEN1RAB9APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | disclosed |