Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874014 | 0.86 | EGFR (0.58) | EGFRPIK3CDPIK3CAIMPDH2FGFR4 | |
| SCHEMBL4985353 | 0.74 | EGFR (0.65) | EGFRPIK3CDPIK3CAIMPDH2ALDH1A1 | |
| SCHEMBL31124778 | 0.74 | EGFR (0.65) | EGFRPIK3CDPIK3CAIMPDH2ALDH1A1 | |
| Hydroquinone SCHEMBL8878778 | 0.74 | EGFR (0.52) | EGFRPIK3CDPIK3CAIMPDH2ALDH1A1 | |
| SCHEMBL5387050 | 0.72 | EGFR (0.42) | EGFRPIK3CDPIK3CAIMPDH2FGFR4 | |
| SCHEMBL30035692 | 0.72 | GRIN2D (0.44) | EGFRPIK3CDPIK3CAALDH1A1BLM | |
| SCHEMBL7222157 | 0.71 | EGFR (0.59) | EGFRPIK3CDPIK3CAALDH1A1POLB | |
| SCHEMBL2190665 | 0.71 | EGFR (0.48) | EGFRPIK3CDPIK3CAIMPDH2FGFR4 | |
| SCHEMBL29551582 | 0.71 | EGFR (0.48) | EGFRPIK3CDPIK3CAALDH1A1HSD17B10 | |
| SCHEMBL28181384 | 0.71 | EGFR (0.48) | EGFRPIK3CDPIK3CAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639881-A | ANTITUMOR AGENTS, TREATMENT OF BREAST CANCER | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-06-17 | — | — | US | disclosed |