Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31124778 | 1.00 | EGFR (0.65) | EGFRPIK3CDPIK3CAPI4KAPI4K2B | |
| SCHEMBL8874014 | 0.86 | EGFR (0.58) | EGFRPIK3CDPIK3CATDO2CSNK1D | |
| SCHEMBL7273128 | 0.83 | EGFR (0.55) | EGFRPIK3CDPIK3CAKDM4EALDH1A1 | |
| SCHEMBL9729774 | 0.83 | CLK1 (0.61) | EGFRPIK3CDPIK3CACSNK1DCSNK1E | |
| SCHEMBL14044871 | 0.82 | EGFR (0.53) | EGFRPIK3CDPIK3CAKDM4EALDH1A1 | |
| Quinazoline SCHEMBL29490398 | 0.79 | EGFR (1.00) | EGFRPIK3CDPIK3CAKDM4ETDO2 | |
| Quinazoline SCHEMBL22833783 | 0.79 | EGFR (1.00) | EGFRPIK3CDPIK3CAKDM4ETDO2 | |
| Quinazoline SCHEMBL5920 | 0.79 | EGFR (1.00) | EGFRPIK3CDPIK3CAKDM4ETDO2 | |
| Quinazoline SCHEMBL29356169 | 0.79 | EGFR (1.00) | EGFRPIK3CDPIK3CAKDM4ETDO2 | |
| SCHEMBL30277791 | 0.79 | NQO2 (0.41) | EGFRPIK3CDPIK3CAPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171874-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | WYETH (US) | 2008-07-17 | — | — | US | claimed |
| US-20060041127-A1 | Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines | WYETH | 2006-02-23 | — | — | US | claimed |
| EP-1345889-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO G]QUINOLINE-3-CARBONITRILES AND BENZO G]QUINAZOLINES | Wyeth (US) | 2003-09-24 | — | — | EP | claimed |
| US-20020091273-A1 | Method for the regioselective preparation of substituted benzo[g]quinoline3-carbonitriles and benzo[g]quinazolines | AMERICAN HOME PRODUCTS CORPORATION | 2002-07-11 | — | — | US | claimed |
| WO-2002053528-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | WYETH (US) | 2002-07-11 | — | — | WO | claimed |
| US-11829036-B2 | Optically anisotropic multilayer product and method for producing same | ZEON CORPORATION (JP) | 2023-11-28 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | SFC CO., LTD. (KR) | 2023-08-03 | — | — | US | disclosed |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | SFC CO., LTD. (KR) | 2023-06-06 | — | — | US | disclosed |
| US-20230002419-A1 | NOVEL BORON COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME | SFC CO., LTD. (KR) | 2023-01-05 | — | — | US | disclosed |
| US-20220411452-A1 | METAL COMPLEX AND APPLICATION THEREOF | GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) | 2022-12-29 | — | — | US | disclosed |
| US-11482676-B2 | Light emitting diode including boron compound | SFC CO., LTD. (KR) | 2022-10-25 | — | — | US | disclosed |
| US-20020091273-A1 | Method for the regioselective preparation of substituted benzo[g]quinoline3-carbonitriles and benzo[g]quinazolines | AMERICAN HOME PRODUCTS CORPORATION | 2002-07-11 | — | — | US | disclosed |
| US-20020091273-A1 | Method for the regioselective preparation of substituted benzo[g]quinoline3-carbonitriles and benzo[g]quinazolines | AMERICAN HOME PRODUCTS CORPORATION | 2002-07-11 | — | — | US | disclosed |
| WO-2002053528-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | WYETH (US) | 2002-07-11 | — | — | WO | disclosed |
| US-6355726-B1 | MULTICOMPONENT UGI REACTION; ANTISENSE AGENTS, ANTIGENS; DIAGNOSIS; CONTROLLING GENE EXPRESSION BY POLYMERIC PEPTIDE NUCLEIC ACIDS | MORPHOCHEM AG (DE) | 2002-03-12 | — | — | US | disclosed |
| WO-2001025213-A2 | PYRROLO IMIDAZOLE DERIVATIVES AND THEIR USE AS MEDICAMENTS | MORPHOCHEM AG (DE) | 2001-04-12 | — | — | WO | disclosed |
| WO-2001025212-A2 | CYCLIC BIPHENYLS, METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS | MORPHOCHEM AG (DE) | 2001-04-12 | — | — | WO | disclosed |
| EP-0983290-A1 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | Morphochem AG (DE) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998051697-A2 | METHOD FOR PRODUCING POLYMERS HAVING NUCLEO-BASES AS SIDE-GROUPS | MORPHOCHEM AG (DE) | 1998-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171874-A1 | METHOD FOR THE REGIOSELECTIVE PREPARATION OF SUBSTITUTED BENZO[G]QUINOLINE-3-CARBONITRILES AND BENZO[G]QUINAZOLINES | PDXK, PKD1, GLS | EGFR 1517/4885PIK3CD 987/4885PIK3CA 478/4885 |
| US-20230002419-A1 | NOVEL BORON COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME | CLTB, CD79B, RB1 | EGFR 2304/4885PIK3CD 2929/4885PIK3CA 2573/4885 |
| US-20220411452-A1 | METAL COMPLEX AND APPLICATION THEREOF | CYBA, IK, COX4I1 | EGFR 3612/4885PIK3CD 3143/4885PIK3CA 3821/4885 |
| US-20230242556-A1 | NOVEL METHOD FOR MANUFACTURING DEUTERATED BORON COMPOUND | BCL6B, BRD7, DBF4 | EGFR 3636/4885PIK3CD 2446/4885PIK3CA 2777/4885 |
| US-20060041127-A1 | Method for the regioselective preparation of substituted benzo[g]quinoline-3-carbonitriles and benzo[g]quinazolines | PDXK, PKD1, GLS | EGFR 1517/4885PIK3CD 987/4885PIK3CA 478/4885 |
| US-20020091273-A1 | Method for the regioselective preparation of substituted benzo[g]quinoline3-carbonitriles and benzo[g]quinazolines | PDXK, PKD1, PFKP | EGFR 1539/4885PIK3CD 1105/4885PIK3CA 532/4885 |
| US-11672172-B2 | Heterocyclic compound comprising aromatic amine group and organic light-emitting diode including the same | DDC, TYR, AOC2 | EGFR 2609/4885PIK3CD 4352/4885PIK3CA 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.