Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862918 | 0.96 | CYP1A2 (0.47) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL11031011 | 0.95 | CYP1A2 (0.46) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL11034112 | 0.95 | CYP1A2 (0.46) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL9436179 | 0.95 | CYP1A2 (0.46) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL9666814 | 0.95 | CYP1A2 (0.46) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL8874236 | 0.84 | MEN1 (0.42) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL11034298 | 0.82 | CYP11B1 (0.47) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL8128286 | 0.82 | NR1I2 (0.55) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 | |
| SCHEMBL9666534 | 0.82 | TSHR (0.50) | CYP19A1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL8134990 | 0.80 | NR1I2 (0.47) | CYP1A2CYP19A1CYP2C9CYP2C19CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |