Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8136926 | 0.85 | NR1I2 (0.45) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL9862969 | 0.84 | ICMT (0.44) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL8874407 | 0.84 | CYP1A2 (0.48) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL9876491 | 0.83 | ICMT (0.44) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL8128286 | 0.83 | NR1I2 (0.55) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL8121009 | 0.83 | MAPT (0.45) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL9863089 | 0.81 | MRGPRX4 (0.42) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL9862918 | 0.81 | CYP1A2 (0.47) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL9666814 | 0.80 | CYP1A2 (0.46) | MEN1KMT2ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL11034112 | 0.80 | CYP1A2 (0.46) | MEN1KMT2ANR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |