SCHEMBL887456

SCHEMBL887456

O=C1c2ccccc2C(=O)N1c1ccc(O)cc1

nearest known ligand 0.79

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 4/20 0.79
ESR1 P03372 5/20 0.71
ESR2 Q92731 3/20 0.71
APAF1 O14727 1/20 0.70
POLB P06746 1/20 0.70
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
SCN2A Q99250 5/20 0.63
CA9 Q16790 3/20 0.63
CA12 O43570 2/20 0.63
CA1 P00915 2/20 0.63
CA2 P00918 2/20 0.63
BRD4 O60885 1/20 0.58
PIM3 Q86V86 1/20 0.54
HIPK4 Q8NE63 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14494705 0.89 NR1H3 (0.66) NR1H3ESR1ESR2APAF1POLB
SCHEMBL15858818 0.89 NR1H3 (0.81) NR1H3ESR1ESR2APAF1POLB
SCHEMBL4649471 0.89 KMT2A (0.78) NR1H3MEN1KMT2ASCN2ACA9
SCHEMBL4580181 0.86 NR1H3 (0.62) NR1H3ESR1ESR2APAF1POLB
SCHEMBL16601645 0.84 POLB (0.85) NR1H3ESR1ESR2APAF1POLB
SCHEMBL5530724 0.83 ESR1 (1.00) NR1H3ESR1ESR2APAF1POLB
SCHEMBL10792923 0.83 POLB (0.70) NR1H3ESR1ESR2APAF1POLB
SCHEMBL12112509 0.83 POLB (1.00) NR1H3ESR1ESR2APAF1POLB
SCHEMBL9277245 0.82 KMT2A (0.69) NR1H3MEN1KMT2ASCN2ACA9
N-Phenyl-Phthalimide SCHEMBL123618 0.81 KMT2A (0.68) NR1H3ESR1MEN1KMT2ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496484-A Bisphenol type polyarylester with high heat resistance and high solubility and preparation method thereof 山东凯盛新材料股份有限公司 2023-07-28 CN claimed
CN-114276530-A Intermittent phosgene interface method preparation process of polycarbonate and application thereof 深圳市德力塑化工科技有限公司 2022-04-05 CN claimed
CN-111793341-A Branched high heat polycarbonate, method of manufacture and articles thereof 沙特基础工业全球技术有限公司 2020-10-20 CN claimed
CN-101005860-A Method of Sterilizing Polycarbonate Articles GEN ELECTRIC (US) 2007-07-25 CN claimed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP claimed
JP-3131631-A None JP disclosed
CN-114846082-B Resin composition and film 株式会社钟化 2024-07-12 CN disclosed
CN-113993831-B Depolymerization of poly (carbonate) and separation of bisphenol A from depolymerized poly (carbonate) 高新特殊工程塑料全球技术有限公司 2024-07-02 CN disclosed
CN-118234805-A Thermoplastic composition and use thereof 高新特殊工程塑料全球技术有限公司 2024-06-21 CN disclosed
CN-118181904-A Multilayer polymeric film and method of making the same 沙特基础工业全球技术有限公司 2024-06-14 CN disclosed
CN-118119656-A Laser transparent low warp glass filled PBT composition for laser welding 高新特殊工程塑料全球技术有限公司 2024-05-31 CN disclosed
CN-118119666-A Thermoplastic composition and use thereof 高新特殊工程塑料全球技术有限公司 2024-05-31 CN disclosed
JP-H03131631-A THERMOPLASTIC LIQUID CRYSTAL WHOLLY AROMATIC POLYIMIDE ESTER AND PRODUCTION THEREOF IDEMITSU PETROCHEM CO LTD 1991-06-05 JP disclosed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP disclosed
EP-0375960-A1 Thermoplastic, liquid-crystalline, wholly aromatic polyimide ester and method of producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1990-07-04 EP disclosed
EP-0161413-B1 WHOLLY AROMATIC POLYESTERS, PROCESS FOR THEIR PREPARATION AND SHAPED ARTICLES MADE THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-18 EP disclosed
US-4737512-A 4-(substituted-isoindol-2-yl)phenoxy-pentanoic and -heptanoic acids and derivatives as anti-arteriosclerotic agents WARNER-LAMBERT COMPANY (US) 1988-04-12 US disclosed
US-4661579-A Completely aromatic polyesters, a process for their preparation and corresponding shaped articles HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
EP-0161413-A1 Wholly aromatic polyesters, process for their preparation and shaped articles made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-21 EP disclosed
US-4393190-A Carbonate copolymers prepared from imide reactants GENERAL ELECTRIC COMPANY (US) 1983-07-12 US disclosed