Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.85 |
| ▸ | APAF1 | O14727 | 1/20 | 0.85 |
| ▸ | ESR1 | P03372 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | USP2 | O75604 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112509 | 0.92 | POLB (1.00) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL7491321 | 0.88 | POLB (0.63) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL31167971 | 0.88 | POLB (0.63) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL887456 | 0.84 | NR1H3 (0.79) | POLBAPAF1ESR1ESR2NR1H3 | |
| SCHEMBL18470167 | 0.84 | POLB (0.82) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL16521594 | 0.82 | POLB (0.68) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL18470152 | 0.82 | POLB (0.79) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL16601986 | 0.82 | CA9 (0.77) | POLBAPAF1KDM4EALDH1A1APOBEC3A | |
| SCHEMBL8615277 | 0.81 | ESR1 (1.00) | POLBAPAF1ESR1NPC1RAB9A | |
| SCHEMBL23312318 | 0.81 | PDE6D (0.63) | POLBAPAF1ESR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |