SCHEMBL8874668

SCHEMBL8874668

O=C1CCCCC1C1=CCC1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.55
CA1 P00915 2/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
KMT2A Q03164 1/20 0.40
MCL1 Q07820 1/20 0.35
MAPT P10636 1/20 0.34
HCAR1 Q9BXC0 2/20 0.33
MAPK1 P28482 1/20 0.31
SLC18A3 Q16572 1/20 0.31
CCR2 P41597 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11443954 0.89 TLR4 (0.58) TLR4CA1CA2CA4KMT2A
SCHEMBL130772 0.88 TLR4 (0.56) TLR4CA1CA2CA4KMT2A
SCHEMBL30130600 0.88 TLR4 (0.56) TLR4CA1CA2CA4KMT2A
SCHEMBL5175094 0.83 TLR4 (0.50) TLR4MAPT
SCHEMBL1964176 0.81 TLR4 (0.48) TLR4CA1CA2CA4KMT2A
Pyridine SCHEMBL28771205 0.77 TLR4 (0.46) TLR4MCL1MAPTKDM4E
SCHEMBL8602853 0.72 CA1 (0.48) TLR4CA1CA2CA4KMT2A
SCHEMBL21053302 0.71
SCHEMBL12019012 0.71 TLR4 (0.40) TLR4CA1CA2CA4KMT2A
SCHEMBL9068672 0.70 KMT2A (0.50) TLR4CA1CA2CA4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-209722082-U A kind of process units of ε-decalactone synthetic perfume ANHUI HUAYE PERFUME HEFEI CO LTD 2019-12-03 CN disclosed
US-5629920-A Photoelectric sensor, information recording system, and information recording method DAI NIPPON PRINTING CO., LTD. (JP) 1997-05-13 US disclosed
US-5488601-A Photoelectric sensor, information recording system, and information recording method DAI NIPPON PRINTING CO., LTD. (JP) 1996-01-30 US disclosed