Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.60 |
| ▸ | FNTB | P49356 | 6/20 | 0.60 |
| ▸ | TACR1 | P25103 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956909 | 0.90 | TACR1 (0.67) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8545840 | 0.90 | TACR1 (0.67) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8875074 | 0.88 | FNTA (0.54) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8875081 | 0.88 | FNTA (0.54) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8875525 | 0.85 | FNTA (0.51) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8956927 | 0.84 | TACR1 (0.64) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8548669 | 0.84 | TACR1 (0.64) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8956821 | 0.83 | TACR1 (0.61) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL8956981 | 0.83 | FNTA (0.62) | FNTAFNTBTACR1KMT2AMEN1 | |
| SCHEMBL7582580 | 0.82 | TACR1 (0.66) | FNTAFNTBTACR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |