Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874760 | 0.92 | PKM (0.63) | SMN1; SMN2PKMKDM4EPOLBUSP2 | |
| SCHEMBL2907457 | 0.82 | PKM (0.75) | SMN1; SMN2PKMKDM4EPOLBUSP2 | |
| SCHEMBL9573627 | 0.80 | PKM (0.52) | SMN1; SMN2PKMKDM4EPOLBCTDSP1 | |
| SCHEMBL5962841 | 0.79 | PKM (0.58) | SMN1; SMN2PKMKDM4EPOLBUSP2 | |
| SCHEMBL5962801 | 0.79 | PKM (0.58) | SMN1; SMN2PKMKDM4EPOLBUSP2 | |
| SCHEMBL8875531 | 0.79 | SMN1; SMN2 (0.82) | SMN1; SMN2PKMKDM4EPOLBCTDSP1 | |
| SCHEMBL23412396 | 0.78 | PKM (0.57) | SMN1; SMN2PKMKDM4EPOLBUSP2 | |
| SCHEMBL15440631 | 0.77 | KDM4E (0.59) | SMN1; SMN2PKMKDM4EPOLBCTDSP1 | |
| SCHEMBL18308364 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2PKMKDM4EPOLBCTDSP1 | |
| SCHEMBL20589803 | 0.76 | POLB (0.50) | SMN1; SMN2PKMKDM4EPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639881-A | ANTITUMOR AGENTS, TREATMENT OF BREAST CANCER | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-06-17 | — | — | US | disclosed |