Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.34 |
| ▸ | RELA | Q04206 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874776 | 1.00 | RARB (0.36) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8875177 | 0.89 | SMN1; SMN2 (0.33) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8875181 | 0.89 | SMN1; SMN2 (0.33) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8875140 | 0.89 | RARB (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8875134 | 0.89 | RARB (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL9724235 | 0.89 | RARB (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8873483 | 0.87 | RARB (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8873490 | 0.87 | RARB (0.39) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8876108 | 0.87 | PTGES (0.33) | RARBNFKB1NFKB2RELANPC1 | |
| SCHEMBL8876114 | 0.87 | PTGES (0.33) | RARBNFKB1NFKB2RELANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641428-A | SHORT SWITCHING TIMES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-24 | — | — | US | disclosed |