Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875566 | 0.77 | CDK1 (0.41) | — | |
| SCHEMBL9600337 | 0.71 | — | — | |
| SCHEMBL612105 | 0.66 | ALDH1A1 (0.34) | KDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL7904142 | 0.66 | CDK1 (0.34) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13339952 | 0.64 | KDM4E (0.33) | KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3421090 | 0.64 | KDM4E (0.33) | KDM4EALDH1A1 | |
| Pbt-434 SCHEMBL7905166 | 0.64 | TLR7 (0.39) | MEN1KMT2A | |
| SCHEMBL17088213 | 0.63 | HDAC6 (0.68) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL31085126 | 0.60 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL10138649 | 0.59 | DHODH (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639881-A | ANTITUMOR AGENTS, TREATMENT OF BREAST CANCER | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-06-17 | — | — | US | disclosed |