Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137127 | 0.97 | AKT1 (0.40) | AKT1CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL8120285 | 0.96 | AKT1 (0.40) | AKT1CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL8134806 | 0.90 | SYK (0.40) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8132756 | 0.89 | SYK (0.40) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL5556101 | 0.86 | CCR6 (0.39) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8135274 | 0.83 | TDP1 (0.34) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL23130693 | 0.83 | AKT1 (0.50) | AKT1NR1D1NR1H3CTSLCTSB | |
| SCHEMBL8018235 | 0.83 | AKT1 (0.50) | AKT1NR1D1NR1H3CTSLCTSB | |
| SCHEMBL8130601 | 0.82 | TDP1 (0.36) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL7203307 | 0.82 | CHRM2 (0.33) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679852-A | Process for the production of DTPA-monoamides of the central carboxylic acid and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-21 | — | — | US | disclosed |
| US-5676923-A | SOLUBLE, STABLE, ORGAN-SPECIFIC NUCLEAR MAGNETIC RESONANCE CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5676926-A | Process for the production of DTPA-tetraesters of terminal carboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-14 | — | — | US | disclosed |
| US-5514810-A | Process for the production of DTPA-tetraesters of terminal carboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-05-07 | — | — | US | disclosed |