Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138668 | 0.88 | NR1I2 (0.54) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL8875264 | 0.86 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL8130662 | 0.85 | NR1I2 (0.43) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL8874130 | 0.83 | CYP3A4 (0.47) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL13623358 | 0.81 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL14007038 | 0.81 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL8875413 | 0.79 | NR1I2 (0.47) | NR1I2CYP3A4CYP2D6GAAMEN1 | |
| SCHEMBL9862923 | 0.78 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6GAARAB9A | |
| SCHEMBL13623369 | 0.76 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL8136112 | 0.76 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5349068-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1994-09-20 | — | — | US | disclosed |