SCHEMBL8875619

SCHEMBL8875619

CSCc1cc(CCCO)on1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.41
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8875233 0.84 PPARA (0.43) PPARAHPGDRAB9A
SCHEMBL25013973 0.77 PPARA (0.41) PPARANOTUM
SCHEMBL8874907 0.77 PPARA (0.41) PPARAHPGDRAB9A
SCHEMBL8876022 0.73 PPARA (0.38) PPARAHPGDRAB9A
SCHEMBL1052595 0.73 VHL (0.44) PPARAHPGDRAB9A
SCHEMBL838157 0.71 SMN1; SMN2 (0.51) PPARARAB9ANOTUM
SCHEMBL4146016 0.70 PPARA (0.41) PPARANOTUM
SCHEMBL18256179 0.69 PPARA (0.43) PPARAHPGDRAB9A
SCHEMBL18914801 0.69 TNKS2 (0.38) PPARA
SCHEMBL1221911 0.69 PPARA (0.61) PPARARAB9ANOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5643929-A TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES SANOFI WINTHROP, INC. (US) 1997-07-01 US disclosed
US-5464848-A 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents STERLING WINTHROP INC. (US) 1995-11-07 US disclosed