Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875619 | 0.84 | PPARA (0.41) | PPARARAB9AHPGD | |
| SCHEMBL8874907 | 0.74 | PPARA (0.41) | PPARARAB9AHPGDS1PR1S1PR3 | |
| SCHEMBL8876022 | 0.71 | PPARA (0.38) | PPARARAB9AHPGD | |
| SCHEMBL1052595 | 0.71 | VHL (0.44) | PPARARAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL18256179 | 0.71 | PPARA (0.43) | PPARARAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL25603631 | 0.70 | PPARA (0.57) | PPARARAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL1221911 | 0.70 | PPARA (0.61) | PPARARAB9ANPC1SMN1; SMN2S1PR1 | |
| SCHEMBL19598757 | 0.69 | PPARA (0.49) | PPARARAB9AHPGDMAPTMAPK1 | |
| SCHEMBL25801694 | 0.69 | PPARA (0.64) | PPARARAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL838157 | 0.69 | SMN1; SMN2 (0.51) | PPARARAB9AMAPK1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |