Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876904 | 0.93 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8875764 | 0.89 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8877500 | 0.88 | ALDH1A1 (0.47) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8875755 | 0.84 | KMT2A (0.52) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8879041 | 0.83 | KMT2A (0.53) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8317246 | 0.82 | KMT2A (0.45) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL9443610 | 0.82 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8877101 | 0.81 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1KDM4E | |
| SCHEMBL8876049 | 0.81 | TSHR (0.48) | KMT2ASMN1; SMN2ALDH1A1TSHRPOLB | |
| SCHEMBL8876411 | 0.81 | KMT2A (0.51) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |