Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874909 | 0.89 | ELANE (0.48) | ELANESCN9AHTR4CNR1CNR2 | |
| SCHEMBL6956554 | 0.87 | KMT2A (0.46) | ELANEHTR4KMT2AKDM4E | |
| SCHEMBL6956867 | 0.87 | KMT2A (0.46) | ELANEHTR4KMT2AKDM4E | |
| SCHEMBL8876561 | 0.87 | ELANE (0.51) | ELANESCN9AHTR4CNR1CNR2 | |
| SCHEMBL6956548 | 0.87 | KMT2A (0.46) | ELANEHTR4KMT2AKDM4E | |
| SCHEMBL6956835 | 0.86 | HTR4 (0.43) | ELANEHTR4KMT2AKDM4E | |
| SCHEMBL6956828 | 0.86 | HTR4 (0.43) | ELANEHTR4KMT2AKDM4E | |
| SCHEMBL6950067 | 0.86 | HTR4 (0.43) | ELANEHTR4KMT2AKDM4E | |
| SCHEMBL4777015 | 0.85 | ELANE (0.55) | ELANESCN9AHTR4KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL27569092 | 0.84 | ELANE (0.54) | ELANESCN9AHTR4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | claimed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |