Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672803 | 0.97 | ACE2 (0.59) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL8875471 | 0.94 | ACE2 (0.56) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL17526233 | 0.89 | HRH3 (0.55) | ACE2PAOXSCN5ASMN1; SMN2HRH3 | |
| SCHEMBL4392341 | 0.87 | ACE2 (0.50) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL5910693 | 0.86 | HRH3 (0.57) | ACE2PAOXSCN5ASMN1; SMN2HRH3 | |
| SCHEMBL13822725 | 0.85 | ACE2 (0.48) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL4396749 | 0.85 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2 | |
| SCHEMBL4393776 | 0.85 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2 | |
| SCHEMBL4396790 | 0.85 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2KDM1A | |
| SCHEMBL18121254 | 0.85 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612329-A | INTERFERENCE WITH CELL GROWTH AND PROLIFERATION | UNIVERSITY OF MARYLAND AT BALTIMORE (US) | 1997-03-18 | — | — | US | disclosed |