Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.59 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876012 | 0.97 | ACE2 (0.56) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL4392341 | 0.89 | ACE2 (0.50) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL5910693 | 0.88 | HRH3 (0.57) | ACE2PAOXSCN5ASMN1; SMN2HRH3 | |
| SCHEMBL13822725 | 0.87 | ACE2 (0.48) | ACE2PAOXSCN5ATP53SMN1; SMN2 | |
| SCHEMBL4396749 | 0.87 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2 | |
| SCHEMBL4396790 | 0.87 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2KDM1A | |
| SCHEMBL4393776 | 0.87 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2 | |
| SCHEMBL18121254 | 0.87 | ACE2 (0.48) | ACE2PAOXTP53SMN1; SMN2 | |
| SCHEMBL17526233 | 0.86 | HRH3 (0.55) | ACE2PAOXSCN5ASMN1; SMN2HRH3 | |
| SCHEMBL17526224 | 0.86 | HRH3 (0.55) | ACE2PAOXSCN5ASMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549761-A4 | METHODS AND COMPOSITIONS FOR THE MODIFICATION OF NUCLEIC ACIDS | VI TECHNOLOGIES INC (US) | 2006-02-15 | — | — | EP | disclosed |
| EP-1549761-A1 | METHODS AND COMPOSITIONS FOR THE MODIFICATION OF NUCLEIC ACIDS | V.I. Technologies, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2005042060-A2 | METHOD AND COMPOSITION COMPRISING PYRUVATE, INOSINE, ADENINE, PHOSPHATE AND AN AZIRIDINO COMPOUND FOR TREATING A BIOLOGICAL SAMPLE | V.I. TECHNOLOGIES, INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20050074743-A1 | Method and composition for treating a biological sample | V.I. TECHNOLOGIES, INC. | 2005-04-07 | — | — | US | disclosed |
| WO-2005002570-A1 | USE OF AN AZIRIDINO COMPOUND TO SELECTIVELY INACTIVATE PARASITES IN BIOLOGICAL COMPOSITIONS | V.I. TECHNOLOGIES, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| EP-1451308-A4 | THERAPEUTIC USE OF AZIRIDINO COMPOUNDS | VI TECHNOLOGIES INC (US) | 2004-11-17 | — | — | EP | disclosed |
| EP-1451308-A2 | THERAPEUTIC USE OF AZIRIDINO COMPOUNDS | V.I. Technologies, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| US-20040053208-A1 | Methods to selectively inactivate parasites in biological compositions | V. I. TECHNOLOGIES, Inc. (US) | 2004-03-18 | — | — | US | disclosed |
| WO-2003093512-A1 | METHODS AND COMPOSITIONS FOR THE MODIFICATION OF NUCLEIC ACIDS | V.I. TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003066806-A2 | THERAPEUTIC USE OF AZIRIDINO COMPOUNDS | V.I. TECHNOLOGIES, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050074743-A1 | Method and composition for treating a biological sample | APOB, MB, ALPP | ACE2 512/4885PAOX 2444/4885SCN5A 4051/4885 |
| US-20040053208-A1 | Methods to selectively inactivate parasites in biological compositions | AZI2, MPO, GZMB | ACE2 1614/4885PAOX 656/4885SCN5A 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.