Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876094 | 1.00 | HPGD (0.63) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL8876632 | 0.88 | HPGD (0.81) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL8876624 | 0.88 | HPGD (0.81) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL8877394 | 0.84 | IGF1R (0.64) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL8876064 | 0.82 | HPGD (0.65) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL8876071 | 0.82 | HPGD (0.65) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL1248799 | 0.80 | CNR1 (0.81) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL1248797 | 0.80 | CNR1 (0.81) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL9433307 | 0.80 | CNR1 (0.81) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL5448423 | 0.79 | HPGD (0.73) | HPGDPTPN1POLBMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594016-A | ANTIDIABETIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0604983-B1 | Naphthalene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0604983-A1 | Naphthalene derivatives | Mitsubishi Chemical Corporation (JP) | 1994-07-06 | — | — | EP | disclosed |