Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | IDH1 | O75874 | 1/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876624 | 0.84 | HPGD (0.81) | HDAC4HDAC8HPGDPTPN1POLB | |
| SCHEMBL8876632 | 0.84 | HPGD (0.81) | HDAC4HDAC8HPGDPTPN1POLB | |
| SCHEMBL8876102 | 0.84 | HPGD (0.63) | HDAC4HDAC8HPGDPTPN1POLB | |
| SCHEMBL8876094 | 0.84 | HPGD (0.63) | HDAC4HDAC8HPGDPTPN1POLB | |
| SCHEMBL18504345 | 0.83 | IDH1 (0.81) | IGF1RHPGDPTPN1POLBMAOA | |
| SCHEMBL1250305 | 0.80 | HPGD (0.74) | ALDH1A1MAPTHPGDPTPN1POLB | |
| SCHEMBL1250306 | 0.80 | HPGD (0.74) | ALDH1A1MAPTHPGDPTPN1POLB | |
| SCHEMBL13846818 | 0.79 | IGF1R (1.00) | IGF1RALDH1A1MAPTHPGDPOLB | |
| SCHEMBL1250598 | 0.79 | IGF1R (1.00) | IGF1RALDH1A1MAPTHPGDPOLB | |
| SCHEMBL1250596 | 0.79 | IGF1R (1.00) | IGF1RALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594016-A | ANTIDIABETIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0604983-B1 | Naphthalene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0604983-A1 | Naphthalene derivatives | Mitsubishi Chemical Corporation (JP) | 1994-07-06 | — | — | EP | disclosed |