Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SPOP | O43791 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674906 | 1.00 | TDP1 (0.60) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8874646 | 0.91 | TDP1 (0.58) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8874653 | 0.91 | TDP1 (0.58) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8877643 | 0.91 | TDP1 (0.57) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8671729 | 0.91 | TDP1 (0.57) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8672307 | 0.89 | NR1I2 (0.60) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8868445 | 0.89 | NR1I2 (0.60) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8673740 | 0.84 | MAPK1 (0.43) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8870510 | 0.84 | MAPK1 (0.43) | TDP1NR1I2HSD17B10PGRALDH1A1 | |
| SCHEMBL8674886 | 0.83 | MAPK1 (0.54) | TDP1NR1I2HSD17B10ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607926-A | ACTIVE AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-03-04 | — | — | US | disclosed |
| US-5604218-A | EXHIBITS ACTIVITY AGAINST METHICILLIN RESISTANT BACTERIA | MICROCIDE PHARMACEUTICALS, INC. (US) | 1997-02-18 | — | — | US | disclosed |