⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trisulfane SCHEMBL737023 | 0.61 | — | — | |
| Trisulfane SCHEMBL36954 | 0.61 | — | — | |
| SCHEMBL36955 | 0.55 | — | — | |
| SCHEMBL2174822 | 0.50 | — | — | |
| SCHEMBL15813254 | 0.50 | — | — | |
| SCHEMBL9820888 | 0.50 | — | — | |
| SCHEMBL11530096 | 0.50 | — | — | |
| SCHEMBL17137757 | 0.50 | — | — | |
| SCHEMBL11850454 | 0.50 | — | — | |
| SCHEMBL4178651 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018325-B2 | 3′-O-modified nucleotide analogues with different cleavable linkers for attaching fluorescent labels to the base for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-06-25 | — | — | US | claimed |
| CN-117320728-A | Use of sialic acid analogues or derivatives | 王慧茹 | 2023-12-29 | — | — | CN | claimed |
| US-20230110712-A1 | SYSTEM AND METHOD FOR CHARACTERIZING PROTEIN DIMERIZATION | REGENERON PHARMACEUTICALS, INC. | 2023-04-13 | — | — | US | claimed |
| US-11525823-B2 | System and method for characterizing protein dimerization | REGENERON PHARMACEUTICALS, INC. (US) | 2022-12-13 | — | — | US | claimed |
| CN-109562142-B | DNA sequencing by synthesis using nucleotide analogs and Raman detection | 纽约哥伦比亚大学董事会 | 2022-09-13 | — | — | CN | claimed |
| CN-114989235-A | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2022-09-02 | — | — | CN | claimed |
| US-20220177959-A1 | HIGH ACCURACY NANOPORE-BASED SINGLE MOLECULE SEQUENCING BY SYNTHESIS WITH TAGGED NUCLEOTIDES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-06-09 | — | — | US | claimed |
| CN-109562376-B | Single molecule/cluster DNA sequencing by synthesis based on fluorescence energy transfer | 纽约哥伦比亚大学董事会 | 2022-03-08 | — | — | CN | claimed |
| US-11225687-B2 | DNA sequencing by synthesis with nucleotide analogues and Raman detection | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-01-18 | — | — | US | claimed |
| CN-113710686-A | Linker and method for optical detection and sequencing | 阿尔缇玛基因组学公司 | 2021-11-26 | — | — | CN | claimed |
| EP-1218391-A1 | COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE | Quiatech AB (SE) | 2002-07-03 | — | — | EP | claimed |
| WO-2001025247-A1 | COMPOUNDS FOR PROTECTING HYDROXYLS AND METHODS FOR THEIR USE | QUIATECH AB (SE) | 2001-04-12 | — | — | WO | claimed |
| EP-0392384-B1 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID CO (US) | 1998-02-18 | — | — | EP | claimed |
| EP-0534742-B1 | Anti-human milk fat globule humanised antibodies | CELLTECH THERAPEUTICS LTD (GB) | 1997-11-19 | — | — | EP | claimed |
| EP-0313873-B1 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID CO (US) | 1994-09-28 | — | — | EP | claimed |
| WO-1993006231-A1 | ANTI-HUMAN MILK FAT GLOBULE HUMANISED ANTIBODIES | CELLTECH LIMITED (GB) | 1993-04-01 | — | — | WO | claimed |
| EP-0534742-A1 | Anti-human milk fat globule humanised antibodies | CELLTECH THERAPEUTICS LIMITED (GB) | 1993-03-31 | — | — | EP | claimed |
| US-5053394-A | Protein-drug reaction product | AMERICAN CYANAMID COMPANY (US) | 1991-10-01 | — | — | US | claimed |
| EP-0392384-A2 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1990-10-17 | — | — | EP | claimed |
| EP-0313873-A1 | Targeted forms of methyltrithio antitumor agents | AMERICAN CYANAMID COMPANY (US) | 1989-05-03 | — | — | EP | claimed |